| |
|
|
|
| You Are Here:
Mesothelioma.net Blog > 2009 > August |
|
Archive for August, 2009
Thursday, August 13th, 2009
The challenge in diagnosing mesothelioma is the symptoms are very common to other, less severe illnesses. Primary symptoms of mesothelioma are the same as a common cold or flu, and include:
- Coughing
- Fever
- Nausea
- Loss of appetite
Unfortunately, the commonality of the symptoms means that mesothelioma is often diagnosed in its late stages, making treatment difficult. The key to a quick and early diagnosis is for your doctor to know that you were exposed to asbestos, the primary cause of mesothelioma.
Fortunately, even after receiving a diagnosis of mesothelioma, you have choices and can determine the best mesothelioma treatment options for your cancer type and stage. Initially, your doctor will run tests such as CT scans and MRI’s to learn more about your condition.
After learning the results of your tests, you and your doctor will need to make decisions regarding your treatment. Do you want to stay with the conventional therapies, such as surgery, chemotherapy drugs and radiation, or do you want to try a more experimental approach, such as gene therapy, or photodynamic therapy (combining certain drugs and light to kill cancer cells)?
If you qualify, there are clinical trials that give you access to treatment programs not available to the general public. Whatever direction you may wish to go, you should consult your medical team and your family to weigh all the options and determine the best course of mesothelioma treatment for you.
Tags: mesothelioma, mesothelioma research, mesothelioma treatment Posted in News | No Comments »
Wednesday, August 12th, 2009
When treating mesothelioma, doctors often recommend more than one treatment, known as multimodality therapy. In the case of early stage malignant pleural mesothelioma, mesothelioma therapies include extrapleural pneumonectomy (EPP), chemotherapy, and radiotherapy (RT).
A recent study was performed on 86 patients with malignant pleural mesothelioma to learn about the effects of RT, and if advanced mesothelioma treatment planning techniques, such as intensity modulated radiotherapy (IMRT) would be beneficial. The study was performed from 1993 to 2008 on patients who underwent EPP followed by hemithoracic RT.
The results showed that no patients died of RT, but that several might have benefitted from receiving IMRT instead of the photon-electron technique they originally received. The study indicated that some patients may receive better coverage from receiving IMRT. The study, published in The Journal of Thoracic Oncology, concluded that the advantages of IMRT should be balanced against the increased risk of fatal pulmonary toxicity.
Consulting with your mesothelioma doctor is critical to determining the best treatment options. There are many medical terms to learn and research to perform to understand what treatment path is the best for you. To maintain all your research and documentation in one place, consider requesting our complimentary Mesothelioma Information Guide. It will help you stay organized and provide one place to document all your notes and medical information.
Tags: mesothelioma, mesothelioma research, mesothelioma treatment Posted in News | No Comments »
Monday, August 10th, 2009
Chemotherapy drugs have different types, many that are used in the treatment of mesothelioma. One of the oldest drugs used to treat cancer are alkylating agents. This agent is toxic to cells, is very reactive, and can give an alkyl group to another compound, such as a cancer cell. Alkylating agents damage DNA preventing a cancer cell from reproducing.
Because alkylating agents are used for lung cancer, they are often used as part of your pleural mesothelioma treatment. The various types include:
- Nitrogen mustards (mechlorethamine, chlorambucil, cyclophosphamide, ifosfamide, and malphalan)
- Nitrosoureas (streptozocin, carmustine, and lomustine)
- Alkyl sulfonates (busulfan)
- Triazines (dacarbazine and temozolomide)
- Ethylenimines (thiotepa and altretamine)
As is common with chemotherapy drugs, alkylating agents are often given in combination with other drugs, such as Alimta, an antifolate. Because of the way the agents damage DNA, they can cause long-term damage to bone marrow, and in rare cases, acute leukemia.
Chemotherapy drugs often have side effects, such as nausea, vomiting, fatigue, weight loss, and hair loss. You should discuss the details of your mesothelioma treatment with your doctor, particularly with regard to any medications you are taking, or any health issues you may have.
We understand you have a lot of questions that require answers in a short period of time. Sometimes it would be nice to speak with someone who can help you sort out the details. Feel free to contact one of our mesothelioma family advocates to ask questions and learn about your options.
Tags: mesothelioma, mesothelioma treatment Posted in News | 2 Comments »
Friday, August 7th, 2009
Doctors will perform various types of surgeries and procedures depending upon the primary goal of your mesothelioma treatment. One example is palliative surgery. Palliative surgery is aimed at relieving the symptoms of mesothelioma and providing relief for the patient.
Paracentesis is a palliative surgery performed on patients of peritoneal mesothelioma, which affects the stomach and abdomen. During this procedure, a long, thin needle is inserted into the belly to drain accumulated fluid. This fluid, known as ascites, can negatively impact the stomach, kidneys and intestines. Draining the ascites provides the mesothelioma patient with relief from the pain and pressure of having extra fluid.
In order to prepare for paracentesis, you need to tell your mesothelioma doctor:
- If you are taking any medication
- If you have any allergic reactions to medicines, including numbing medicines
- If you have any bleeding problems, or are taking blood thinners or aspirin
- If you are pregnant
Your doctor will numb the area before inserting the needle, and then drain the fluid. Depending upon the amount of fluid to be drained, the procedure can take anywhere from a few minutes to days. Paracentesis can be performed in the doctor’s office, the hospital or an emergency room.
Remember to follow your post-operative care instructions carefully, and let your doctor know of any issues you have after the procedure. Also, make sure to document all the information you receive during and after the procedure for future reference.
Tags: mesothelioma, mesothelioma treatment Posted in Treatments | No Comments »
Thursday, August 6th, 2009
CBP501 is entering Phase II trials for the treatment of non-small cell lung cancer. This chemotherapy drug is also undergoing Phase II trials for the treatment of malignant pleural mesothelioma. Pre-clinical information implies that CBP501 has the potential to cause cancer cell death by blocking the cancer cells from completing their cell cycle. The Phase I study showed that it may augment anti-cancer cytotoxicity when combined with other chemotherapy drugs.
CBP501 is being developed through collaboration between Japanese companies, CanBas Co., LTD, Takeda Pharmaceutical Company and Takeda’s wholly-owned subsidiary Millennium.
Information on the clinical trial for CBP501 can be found at the ClinicalTrials.gov site. For more information on available clinical trials, see our list or contact one of our mesothelioma family advocates.
Tags: mesothelioma, mesothelioma treatment Posted in News | No Comments »
|
|
|
|
|
|